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Pergolide
Pergolide (marketed as Permax) is a dopamine agonist drug (DA) used in the treatment of the tremor and slowness associated with Parkinson's disease. The drug was approved for use in 1988 and is manufactured by Valeant Pharmaceuticals. In 2007, the federal Food and Drug Administration (FDA) published a public health advisory warning patients against Pergolide after a study by the New England Journal of Medicine implicated that a previously unknown Pergolide side effect was heart valve damage. Patients who are taking Pergolide are warned to discontinue use with a doctor's assistance.
Fast Facts
| Name: | Permax |
| Generic: | Pergolide |
| Manufacturer: | Valiant Pharmaceuticals, Par, Teva |
| Date approved: | 1988 |
| Status: | Voluntary market withdrawal after FDA alert |
| Approved uses: | Treatment of symptoms of Parkinson's disease, including tremors and slow movements |
| Off-Label uses: | Treatment of restless leg syndrome |
| Side effects: | Pergolide can cause side effects, including disrupted digestion, nervous symptom complaints like hallucinations or insomnia, and rhinitis. In 2007, Pergolide was linked to severe heart valve damage in some patients and withdrawn from the market. |
| Related topics: | Procrit, Vioxx |
Parkinson's Drug Pergolide (Permax) Taken Off Shelves
A federal Food and Drug Administration (FDA) report of recent studies has demonstrated the dangers of Pergolide (Permax) to patients with Parkinson's disease. Now manufacturers Valeant... read more
Pergolide Recall: What's Next for Parkinson's Patients?
With the recent recall of Pergolide from store shelves after the drug (also marketed as Permax) was linked to heart valve damage in two recent studies. But now that the Pergolide recall is in... read more
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FDA Information Related to Pergolide
FDA Clears First Respirators for Use in Public Health Medical Emergencies
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MSN Newsfeeds Related to Pergolide
Patients to launch class action over Parkinson's drug
Patients to launch class action over Parkinson's drug
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News Articles Related to Pergolide
Equine Advocates to Host Awards Dinner | bloodhorse.com
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Useful Web Sites Related to Pergolide
Anapol Schwartz Lawyers - Pennsylvania Pergolide/Permax Lawsuits
View the Pergolide Useful Web Sites page here
Books Related to Pergolide
View the Pergolide Books page here
