Pergolide (marketed as Permax) is a dopamine agonist drug (DA) used in the treatment of the tremor and slowness associated with Parkinson's disease. The drug was approved for use in 1988 and is manufactured by Valeant Pharmaceuticals. In 2007, the federal Food and Drug Administration (FDA) published a public health advisory warning patients against Pergolide after a study by the New England Journal of Medicine implicated that a previously unknown Pergolide side effect was heart valve damage. Patients who are taking Pergolide are warned to discontinue use with a doctor's assistance.
Parkinson's Drug Pergolide (Permax) Taken Off Shelves
A federal Food and Drug Administration (FDA) report of recent studies has demonstrated the dangers of Pergolide (Permax) to patients with Parkinson's disease. Now manufacturers Valeant Pharmaceuticals, Teva and Par have pulled the drug from shelves in just one of a recent spate of voluntary recalls. The drug, a so-called dopamine agonist (DA) that helps to calm tremors and increase balance in Parkinson's patients, has been linked to dangerous side effects, including an increased risk of heart valve damage in some patients.
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Pergolide Recall: What's Next for Parkinson's Patients?
With the recent recall of Pergolide from store shelves after the drug (also marketed as Permax) was linked to heart valve damage in two recent studies. But now that the Pergolide recall is in effect, what comes next for patients who suffer from Parkinson's disease. Pergolide (Permax) was relied upon by nearly 25,000 Parkinson's patients to quell tremors and restore normal balance and movement associated with the nerve disorder.
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